Pharmacophore
Pharmacophore, represents the spatial arrangement of features that is essential for a molecule to interact with a specific target receptor, is an alternative method despite molecular docking for achieving this goal.
Different types of pharmacoiphore searching softwares:
| Software | Description |
|---|---|
| Pharmer | It is efficient pharmacophore tool for virtual screening and it takes only one pdb file at a time. |
| Pharmapper | It contains a database repository of about 7000 targets based pharmacophore models. Based on triangle hashing based method, it finds the best matching poses of input ligand against all known pharmacophore based models. |
| PharmaGist | PharmaGist used for searching pharmacophore from a set of ligand molecules. It requires the set of ligands known to interact with a particular target without any prior knowledge of target structure. |
| Boomer | It is freely available pharmacokinetic drug monitering. |
| ZincPharma | It is used for screening of zinc database. |
| PKfit | PKfit is a tool for pharmacokinetic modeling. |
| JPKD | It is a therapeutic drug monitoring tool. |